Partner Profile

Laboratory for Muscle Plasticity


Areas of Expertise

The Laboratory for Muscle Plasticity at Balgrist University Hospital investigates the molecular and cellular mechanisms of clinical muscle plasticity. Towards this end we carry out clinical trials investigating biological relationships between muscle and clinical endpoints of musculoskeletal disease from molecule to movement. Identified factors are probed for their mechanistic role in disease onset and propagation with gene pharmacological means in animal models, before being reintegrated in a clinical context. The aim is to improve current treatments for musculoskeletal affections.

Recent Publications

Client Presentations
A quest into muscle plasticity
A quest into muscle plasticity

Professor Martin Fluck expands upon the quest for muscle plasticity with the aim of encouraging further innovative surgical and rehabilitative approaches to maximise quality of life for handicapped individuals...[]

Research Interests

Main topics include:

  • Muscle degeneration (atrophy and fat infiltration) with rupture of rotator cuff tendons;
  • Biomarkers of success in rotator cuff repair;
  • Muscle alterations with patellofemoral instability;
  • Gene therapy of muscle degeneration with Achilles tendon rupture;
  • Genome-based personalisation of muscle rehabilitation; and
  • Adhesion-mediated mechano-regulation of muscle plasticity.