Laboratory for Muscle Plasticity
The Laboratory for Muscle Plasticity at Balgrist University Hospital investigates the molecular and cellular mechanisms of clinical muscle plasticity. Towards this end we carry out clinical trials investigating biological relationships between muscle and clinical endpoints of musculoskeletal disease from molecule to movement. Identified factors are probed for their mechanistic role in disease onset and propagation with gene pharmacological means in animal models, before being reintegrated in a clinical context. The aim is to improve current treatments for musculoskeletal affections.
- Profile in Horizon2020 Projects Portal – Issue 8
- Profile in Pan European Networks Government – issue 16
- Profile in Horizon2020 Projects Portal – Issue 7
A quest into muscle plasticity
Professor Martin Fluck expands upon the quest for muscle plasticity with the aim of encouraging further innovative surgical and rehabilitative approaches to maximise quality of life for handicapped individuals...[]
Main topics include:
- Muscle degeneration (atrophy and fat infiltration) with rupture of rotator cuff tendons;
- Biomarkers of success in rotator cuff repair;
- Muscle alterations with patellofemoral instability;
- Gene therapy of muscle degeneration with Achilles tendon rupture;
- Genome-based personalisation of muscle rehabilitation; and
- Adhesion-mediated mechano-regulation of muscle plasticity.